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Oxaloacetate May Ease Chemo Brain After Breast Cancer

A UCLA Health Jonsson Comprehensive Cancer Center-led study found that an oxaloacetate supplement may improve cognitive function and reduce fatigue in some breast cancer survivors after treatment.

By MediIndex NewsroomU&U Breast Health Times
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Illustration of a diagnostic imaging room, generated for this article

Researchers led by the UCLA Health Jonsson Comprehensive Cancer Center studied a nutritional supplement containing oxaloacetate, a molecule naturally present in the body that helps cells produce energy. Their findings suggest that the supplement may help ease post-treatment brain fog and fatigue for some breast cancer survivors.

What the study found

The UCLA-led team linked the oxaloacetate supplement with possible improvements in cognitive function and fatigue after breast cancer treatment. The finding concerns symptoms commonly described as chemo brain or brain fog rather than treatment of the cancer itself.

How to interpret the finding

The researchers framed the benefit as a possibility for some breast cancer survivors. That wording reflects uncertainty and does not establish that every survivor will experience cognitive or fatigue improvement from oxaloacetate.

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